| 产品详情 |
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| Antigenic Specificity | PTPN11 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1κ |
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| Format | purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. This PTPN11 monoclonal antibody is generated from mouse immunized with PTPN11 recombinant protein. |
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| Immunogen | Human PTPN11. |
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| Other Names | BPTP3; CFC; MGC14433; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2; SH-PTP; PTPN11; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); SHP-2; Noonan syndrome 1; protein tyrosine phosphatase, non-receptor type 11; PTP-2C |
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| Gene, Accession # | SwissProt: Q06124 |
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| Catalog # | abx025290 |
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| Price | |
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| Order / More Info | PTPN11 Antibody from ABBEXA |
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| Product Specific References | n/a |
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