| 产品详情 |
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| Product Name | AVL-292 |
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| Description | A selective, irreversible inhibitor of BTK (IC50 = 0.5 nM in vitro in B cell lymphoma cell lines) that targets and covalently binds to BTK at cysteine-481; inhibits osteoclast function and reduces osteoclast-stimulated proliferation of multiple myeloma cells in animal models of rheumatoid arthritis and multiple sclerosis; demonstrates therapeutic significance in clinical trials for the treatment of B cell-related cancers and autoimmune diseases |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CC-292|Spebrutinib |
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| Gene, Accession, CAS # | CAS: 1202757-89-8 |
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| Catalog # | 17993-5 |
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| Price | |
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| Order / More Info | AVL-292 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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