产品名称 NIK Antibody from BIOVISION, INC.
产品货号 3193-100
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 BIOVISION, INC.
产品概述
产品详情
Edit&nbsp
Antigenic SpecificityNIK
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size100 µg
Concentration0.2 mg/ml
ApplicationsWestern blot
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPolyclonal Antibody to detect NIK in Human, Mouse, Rat samples. NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK was initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecular weight of slightly more than 97 kDa on SDS gel. NIK is a serine/threonine kinase and its kinase activity contributes to IkB phosphorylation. The carboxyl terminal segment of NIK binds TRAF2. A mutant NIK with intact carboxyl terminus but without the two lysine residues at its catalytic domain serves as a dominant-negative inhibitor for NF-kB activation. NIK also interacts with TRAF6 and mediates IL-1-induced NF-kB activation.
ImmunogenE. coli expressed recombinant human NIK fragment (a.a. 795-947).
Other NamesMAP3K14
Gene, Accession #Gene ID: 9020, Accession: Q99558
Catalog #3193-100
Price
Order / More InfoNIK Antibody from BIOVISION, INC.
Product Specific Referencesn/a
产品资料