| 产品详情 |
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| Antigenic Specificity | SFTPC |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | 1.0 mg/ml |
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| Applications | ELISA, WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. |
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| Immunogen | Purified recombinant fragment of human SFTPC (AA: 60-180) expressed in E. Coli. |
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| Other Names | Pulmonary surfactant-associated protein C; SP-C; SFTPC; SFTP2; Pulmonary surfactant-associated proteolipid SPL(Val); SP5; Pulmonary surfactant-associated proteolipid SPL (Val); PSP-C; SMDP2; BRICD6 |
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| Gene, Accession # | SFTPC, Gene ID: 6440, SwissProt: P11686 |
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| Catalog # | abx012157 |
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| Price | |
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| Order / More Info | SFTPC Antibody from ABBEXA |
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| Product Specific References | n/a |
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