| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | NR1I3 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 50 µl, 100 µl, 200 µl |
|---|
| Concentration | > 1 mg/ml |
|---|
| Applications | WB, IF/ICC. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | NR1I3 Antibody is a Rabbit Polyclonal antibody against NR1I3. This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. |
|---|
| Immunogen | Recombinant protein of human NR1I3. |
|---|
| Other Names | CAR; CAR1; MB67; Constitutive androstane receptor; Orphan nuclear receptor MB67; Orphan nuclear receptor NR1I3; Constitutive Activator Of Retinoid Response; Constitutive Active Response; Nr1I3 |
|---|
| Gene, Accession # | NR1I3, Gene ID: 9970, SwissProt: Q14994 |
|---|
| Catalog # | abx001605 |
|---|
| Price | |
|---|
| Order / More Info | NR1I3 Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|