| 产品详情 |
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| Antigenic Specificity | NR1I2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NR1I2 Antibody is a Rabbit Polyclonal antibody against NR1I2. This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. |
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| Immunogen | Recombinant protein of human NR1I2. |
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| Other Names | BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq; NR1I2; Nuclear receptor subfamily 1 group I member 2; Orphan nuclear receptor PAR1; Orphan nuclear receptor PXR; Pregnane X receptor; Steroid and xenobiotic receptor; nuclear receptor subfamily 1, group I, member 2; orphan nuclear receptor |
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| Gene, Accession # | NR1I2, Gene ID: 8856, SwissProt: O75469 |
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| Catalog # | abx001333 |
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| Price | |
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| Order / More Info | NR1I2 Antibody from ABBEXA |
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| Product Specific References | n/a |
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