| Edit |   |
| Antigenic Specificity | HAVCR2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl |
| Concentration | n/a |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD4 (MIM 186940) positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2. |
| Immunogen | Human HAVCR2. |
| Other Names | HAVCR2; TIM3; TIMD3; Hepatitis A virus cellular receptor 2; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell membrane protein 3; TIM-3; KIM-3; T-cell immunoglobulin mucin receptor 3; TIMD-3; HAVcr-2 |
| Gene, Accession # | HAVCR2, SwissProt: Q8TDQ0 |
| Catalog # | abx031327 |
| Price | |
| Order / More Info | HAVCR2 Antibody from ABBEXA |
| Product Specific References | n/a |