| 产品详情 |
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| Product Name | Pasireotide (aspartate) |
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| Description | An SSTR agonist; binds selectively to human SST1, SST2, SST3, and SST5 over SST4 (IC50s = 9.3, 1, 1.5, 0.16, and >100 nM, respectively, for human recombinant receptors); dose-dependently inhibits GHRH-stimulated growth hormone release by primary rat anterior pituitary cells; inhibits ACTH secretion by some primary human corticotrope adenomas (10 nM); inhibits ACTH release and proliferation by mouse AtT20 pituitary corticotrope cells in vitro (10 nM); inhibits tumor growth of subcutaneously implanted AtT20 cells in vivo in nude mice (1.5 µg per day); decreases plasma ACTH concentrations and tumor size in dogs with ACTH-dependent Cushing's disease (0.03 mg/kg) |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SOM230 |
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| Gene, Accession, CAS # | CAS: 820232-50-6 |
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| Catalog # | 24092-5 |
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| Order / More Info | Pasireotide (aspartate) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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