产品详情 |
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Antigenic Specificity | Disialoganglioside GD3 |
Clone | MB3.6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG3, kappa |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Disialoganglioside GD3 Monoclonal Antibody (MB3.6), eBioscience™. Disialoganglioside GD3 is a membrane-bound sialic acid-containing glycosphingolipid. Gangliosides are synthesized in the Golgi apparatus by glycosyltransferases before localizing to the plasma membrane. Gangliosides function as receptors for growth factors and hormones as well as mediating interaction with adhesion molecules at the surface of all cells. GD3 is expressed at low levels in retina pigment cells and melanocytes. Elevated GD3 levels are found in neural stem cells, epithelial-origin tumor cells (cervical, ovarian, prostate, breast, and skin), as well as T-cell leukemic lymphoblasts (T-ALL). |
Immunogen | n/a |
Other Names | Ganglioside GD3; ST8 alpha-2,8-Sialyltransferase 8A; ST8SIA1; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1 |
Gene, Accession # | n/a |
Catalog # | 14-9754-80 |
Price | |
Order / More Info | Disialoganglioside GD3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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