产品详情 |
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Product Name | C-DIM5 |
Description | A Nur77 receptor agonist; selectively activates Nur77 over PPARγ in reporter assays at 20 µM; inhibits growth of and induces apoptosis in L3.6pL pancreatic cancer cells at 10, 15, and 20 µM; stabilizes nuclear localization of Nur77 and Nurr1 and reduces secretion of pro-inflammatory cytokines in primary mouse astrocytes; oral administration prevents loss of dopaminergic neurons in the substantia nigra pars compacta and striatal dopamine terminals in a mouse model of MPTP-induced Parkinson's disease at 50 mg/kg, |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | DIM-C-pPhOCH3 |
Gene, Accession, CAS # | CAS: 33985-68-1 |
Catalog # | 27980-10 |
Price | |
Order / More Info | C-DIM5 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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