| 产品详情 |
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| Antigenic Specificity | CD45 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, monkey |
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| Isotype | IgG1 |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The CD45 molecule is also known as the Leukocyte Common Antigen (LCA) or T200 antigen, and is comprised of different glycoproteins ranging from 180-240 kDa. Expression of CD45 is found on all hemopoietic cells, e.g. granulocytes, monocytes, macrophages and lymphocytes, except mature erythroid cells. Detection of the different isoforms can distinguish, for example, between naive T cells and memory T cells, which is of interest in patients with immunodeficiency and autoimmune diseases. The CD45 (HI30) antibody recognizes the 180, 190, 205 and 220-kDa long single chain type I transmembrane glycoprotein called leukocyte common antigen (LCA). LCA is typically expressed at high levels on all nucleated hematopoietic cells including bone marrow cells, thymocytes, lymphocytes, monocytes, granulocytes, but not on mature erythrocytes, platelets and non-hematopoietic tissues and cells. CD45 is critically required for T and B cell antigen receptor-mediated activation. |
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| Immunogen | Human Peripheral Blood Leucocytes. |
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| Other Names | CD45; B220; CD45R; CD45RA; CD45RB; CD45RC; CD45RO; LCA; T200; Ly5; Leukocyte common antigen; L-CA; MAB TO CD45; Leukocyte Common Antigen (LCA); Receptor-type tyrosine-protein phosphatase C; CD antigen CD45; GP180; PTPRC |
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| Gene, Accession # | Gene ID: 5788, SwissProt: P08575 |
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| Catalog # | abx200309 |
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| Price | |
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| Order / More Info | CD45 Antibody from ABBEXA |
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| Product Specific References | n/a |
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