产品名称 Glial Fibrillary Acidic Protein (GFAP) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN571886
产品价格 现货询价,电话:010-67529703
产品规格 100 µL
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityGlial Fibrillary Acidic Protein (GFAP) (C-Term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat, human
Isotypen/a
Formatserum
Size100 µL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC),Western Blotting (WB)
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DescriptionFunction: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Defects in GFAP are a cause of Alexander disease (ALEXD). Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.Subcellular location: Cytoplasm. Note: Associated with intermediate filaments Tissue expression: Expressed in the cortex and hippocampus. Expression decreases following acute and chronic corticosterone treatment, expressed in astrocytes, in satellite cells and in non-myelinating Schwann cells Also known as: Glial fibrillary acidic protein.
ImmunogenA synthetic peptide from c-terminal region of mouse GFAP (Glial fibrillary acidic protein) conjugated to an immunogenic carrier protein was used as the antigen.
Other NamesGFAP|AI836096|cb345|etID36982.3|gfapl|wu:fb34h11|wu:fk42c12|xx:af506734|zgc:110485
Gene, Accession #Gene ID: 2670,14580,24387
Catalog #ABIN571886
Price
Order / More InfoGlial Fibrillary Acidic Protein (GFAP) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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