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| Product Name | S63845 |
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| Description | An Mcl-1 inhibitor (Ki = 0.19 nM); induces cell death in multiple myeloma, leukemia, and lymphoma cell lines (IC50s = via mitochondrial apoptosis; acts synergistically with trametinib, lapatinib, PLX4032, and erlotinib to reduce proliferation of SK-MEL-2, BT474, A2058, and PC9 cells, respectively; reduces tumor volume in a MV4-11 acute myeloid leukemia mouse xenograft model in a dose-dependent manner |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Mcl1 S-63845 PLX-4032 SKMEL2 BT-474 A-2058 PC-9 |
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| Gene, Accession, CAS # | CAS: 1799633-27-4 |
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| Catalog # | 21131-1 |
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| Price | |
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| Order / More Info | S63845 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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