| 产品详情 |
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| Antigenic Specificity | BCL10 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | 1.0 mg/ml |
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| Applications | ELISA, WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN.Entrez Protein NP_003912.It is a protein containing a caspase recruitment domain (CARD).It plays an important role in apoptosis and activating NF-kappaB.The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling.Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma.MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. |
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| Immunogen | Purified recombinant fragment of human BCL-10 expressed in E. coli. |
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| Other Names | B-cell CLL/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; CARD- containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; CED- 3/ICH-1 prodomain homologous E10-like regulator; CIPER; CLAP; Cellular homolog of vCARMEN; Cellular-E10; Mammali; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; cCARMEN; c-E10; Mammalian CARD-containing adapter molecule E10; mE10; CARMEN |
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| Gene, Accession # | Gene ID: 8915 |
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| Catalog # | abx015774 |
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| Price | |
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| Order / More Info | BCL10 Antibody from ABBEXA |
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| Product Specific References | n/a |
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