| 产品详情 |
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| Antigenic Specificity | RHEB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2 µg/mL, Western Blot: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RHEB Polyclonal Antibody. Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability o |
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| Immunogen | n/a |
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| Other Names | RHEB2; GTP-binding protein Rheb; Ras homolog enriched in brain 2 |
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| Gene, Accession # | Entrez: 19744, 6009; Uniprot: Q15382, Q921J2 |
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| Catalog # | PA5-20129 |
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| Price | |
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| Order / More Info | RHEB Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24806451 |
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