产品详情 |
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Antigenic Specificity | Leptin |
Clone | 3G7 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Leptin Monoclonal Antibody (3G7). Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function. Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene. Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body. Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta. Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells. Leptin's effects on body weight are mediated through effects on hypothalamic center |
Immunogen | n/a |
Other Names | LEP-R, Obesity factor, obesity protein, OB-R, HuB219, CD295 antigen |
Gene, Accession # | Entrez: 3952; Uniprot: P41159 |
Catalog # | MA1-22083 |
Price | |
Order / More Info | Leptin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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