| 产品详情 |
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| Antigenic Specificity | NTAL/LAT2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Linker for activation of T-cells family member 2(LAT2) detection. Tested with WB in Human. No cross reactivity with other proteins. LAT2(Linker for Activation of T Cells Family, Member 2), also known as LAB or NTAL , is a protein that in humans is encoded by the LAT2 gene. By genomic sequence analysis, Doyle et al.(2000) mapped the WBSCR5 gene to chromosome 7q11.23. They noted that the flanking genes are highly conserved between mouse and human. By immunoprecipitation and immunoblot analysis, Brdicka et al.(2002) found that NTAL associated with GRB2, SOS1, and GAB1 after B-cell receptor activation. Janssen et al.(2003) determined that phosphorylation of LAB is likely mediated by SYK upon B-cell receptor stimulation. Binding analysis indicated associations with GRB2, and, indirectly, with PLCG1 and PLCG2. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human NTAL(34-48aa KRSEKIYQQRSLRED). |
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| Other Names | Linker for activation of T-cells family member 2;Linker for activation of B-cells;Membrane-associated adapter molecule;Non-T-cell activation linker;Williams-Beuren syndrome chromosomal region 15 protein;Williams-Beuren syndrome chromosomal region 5 protein;LAT2;LAB, NTAL, WBS15, WBSCR15, WBSCR5;HSPC046; |
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| Gene, Accession # | LAT2, UniProt: Q9GZY6 |
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| Catalog # | PA2039 |
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| Price | |
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| Order / More Info | NTAL/LAT2 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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