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| Product Name | Trequinsin (hydrochloride) |
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| Description | A cAMP-dependent PDE3 inhibitor (IC50s = 0.04 and 0.03 nM for PDE3A and PDE3B, respectively in T84 cell lysates); stimulates cAMP accumulation (10 µM) and increases membrane capacitance in rat juxtaglomerular cells; competitively inhibits multidrug resistant protein 5-mediated export of cGMP from Chinese hamster lung fibroblasts (Ki = 240 nM); reduces collagen-induced platelet aggregation in rabbits (3 µg/kg per minute); reduces collagen-induced decreases in mean arterial blood pressure alone or in combination with prostacyclin |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 79855-88-2 HL725 T-84 PDE-3A 3B 3 HL-725 PDE3 MDR5 MDR-5 |
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| Gene, Accession, CAS # | CAS: 78416-81-6 |
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| Catalog # | 17217-10 |
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| Order / More Info | Trequinsin (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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