| 产品详情 |
| Edit |   |
|---|
| Product Name | SR8278 |
|---|
| Description | An antagonist of REV-ERBα (EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112; stimulates the expression of the REV-ERBα target genes G6Pase and PEPCK in liver cells; used to elucidate the role of REV-ERBα in regulating glucagon secretion in pancreatic alpha cells |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 1426385-65-0 biochemical receptor antagonist nuclear gene regulation signal transduction intracellular signaling metabolism circadian clock metabolic syndrome carbohydrate research diabetes REV-ERBα GSK 4112 REVERBα GSK4112 SR8278 G6Pase PEPCK liver cell glucagon secretion pancreatic pancreas alpha glucose 6-phosphatase phosphoenolpyruvate carboxykinase |
|---|
| Gene, Accession, CAS # | CAS: 1254944-66-5 |
|---|
| Catalog # | 17000-25 |
|---|
| Price | |
|---|
| Order / More Info | SR8278 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|