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| Product Name | Skepinone-L |
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| Description | An ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50s = 5 nM) and p38β (97% inhibition at 1 µM); has little effect on a range of other kinases, including p38γ and p38δ; blocks the phosphorylation of HSP27, a p38 MAPK substrate, in response to stimulation with anisomycin in HeLa cells (IC50 = 25 nM) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical inhibitor kinase protein intracellular signaling inhibit ATP-competitive p38α MAPK mitogen-activated isoform p38β block phosphorylation heat shock 27 HSP27 HSP substrate anisomycin HeLa cell TNF-α THP-1 TNFα THP1 cytosolic phospholipase A2 cPLA2 platelet collagen-related peptide thrombin blunting secretion aggregation |
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| Gene, Accession, CAS # | CAS: 1221485-83-1 |
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| Catalog # | 16974-10 |
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| Price | |
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| Order / More Info | Skepinone-L from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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