产品详情 |
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Product Name | CP 43 |
Description | Potent TAO kinase (TAOK) inhibitor (IC50 values are 11 nM/L and 15 nM/L for TAOK1 and TAOK2, respectively). Inhibits TAOK phosphorylation and activation of JNK in vitro. Prolongs duration of mitosis and increases mitotic cell death in the SKBR3 breast cancer cell line. Also reduces tau phopshorylation in cortical neurons at sites associated with neurodegeneration in human tauopathies. Purity 98%. MW (observed): 384.47 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide |
Gene, Accession, CAS # | CAS: 850467-66-2 |
Catalog # | 6558/50 |
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Order / More Info | CP 43 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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