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Product Name | CP 154526 |
Description | Selective, non-peptide CRF1 receptor antagonist (Ki values are 2.7 and > 10000 nM for CRF1 and CRF2 receptors respectively). Blocks CRF-induced adenylate cyclase activation (Ki = 3.7 nM) and attenuates activation of the HPA axis by CRF. Displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant. Purity 99%. MW (observed): 400.99 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride |
Gene, Accession, CAS # | CAS: 257639-98-8 |
Catalog # | 2779/10 |
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Order / More Info | CP 154526 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 26630389 |
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