产品详情 |
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Antigenic Specificity | CCR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 5-10 µL/test, Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR1 Polyclonal Antibody. Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation. |
Immunogen | n/a |
Other Names | CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 |
Gene, Accession # | Entrez: 1230, 12768; Uniprot: P32246, P51675 |
Catalog # | PA1-41062 |
Price | |
Order / More Info | CCR1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 27167205 |
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