| 产品详情 |
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| Antigenic Specificity | CCR1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 2.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCR1 Polyclonal Antibody. Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation. |
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| Immunogen | n/a |
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| Other Names | CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 |
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| Gene, Accession # | Entrez: 1230; Uniprot: P32246 |
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| Catalog # | PA5-33392 |
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| Price | |
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| Order / More Info | CCR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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