| Edit |   |
| Antigenic Specificity | CD45RA |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | FCM. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Human CD45RA is expressed on all cells of hematopoietic origin, except erythrocytes. CD45RA is a transmembrane tyrosine phosphate which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RA isoform predominates on naive/resting T cells and medullary thymocytes. This GRT22 monoclonal antibody reacts with human and non-human primate CD45RA, a 220 kDa moleculeexpressed by subpopulations of CD4+ and CD8+ naive peripheral T lymphocytes and B cells.The GRT22 antibody crossreacts to rhesus CD45RA. Crossblocking studies indicate that GRT22 and HI100recognize different epitopes |
| Immunogen | Tissue / cell preparation (Human). Fresh human lymph node lymphocytes depleted of surface immunoglobulin positive cells were used as the immunogen. This antigen is a single chain glycoprotein which is expressed on B cells, monocytes, and T cell subsets. |
| Other Names | CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45; CD45RA; B220; CD45R; CD45RB; CD45RC; CD45RO; LCA; Ly5 |
| Gene, Accession # | Gene ID: 5788, SwissProt: P08575 |
| Catalog # | abx200320 |
| Price | |
| Order / More Info | CD45RA Antibody from ABBEXA |
| Product Specific References | n/a |