产品详情 |
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Product Name | MX69 |
Description | An inhibitor of the MDM2 protein and XIAP mRNA interaction; binds to the RING domain of MDM2 (Kd - 2.34 µM); decreases the levels of MDM2 and XIAP; induces autoubiquitination and degradation of MDM2 and increases the half-life of p53 in EU-1 cells; cytotoxic to a variety of ALL and neuroblastoma cancer cell lines but not to NBMM cells; increases survival in an EU-1 mouse model of leukemia at 100 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 1005264-47-0 |
Catalog # | 27224-1 |
Price | |
Order / More Info | MX69 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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