| 产品详情 |
| Edit |   |
|---|
| Product Name | SSR 69071 |
|---|
| Description | High affinity, potent inhibitor of human leukocyte elastase (HLE) (IC50 = 3.9 nM). Displays species-selectivity (Ki values are 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase respectively). Inhibits HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduces infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Orally active. Purity 98%. MW (observed): 556.63 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)ethoxy]-4H-pyrido[1,2-a]pyrimidin-4-one |
|---|
| Gene, Accession, CAS # | CAS: 344930-95-6 |
|---|
| Catalog # | 2506/10 |
|---|
| Price | |
|---|
| Order / More Info | SSR 69071 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 21693707, 21820333, 24023624 |
|---|
| 产品资料 |
|
|