| 产品详情 |
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| Product Name | SSR 149415 |
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| Description | Potent and selective vasopressin V1B antagonist (Ki values are 3.7 and 1.3 nM for native and recombinant rat V1b receptors, respectively). Displays >70-fold selectively for rat V1B over V1A, V2 oxytoxin and a range of other receptors and ion channels. Inhibits AVP-induced glucagon release in In-R1-G9 α-pancreatic cells in vitro. Inhibits stress-induced ACTH release and exhibits anxiolytic-like effects in anxiety models. Orally bioavailable. Purity 98%. MW (observed): 630.11 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide. Nelivaptan |
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| Gene, Accession, CAS # | CAS: 439687-69-1 |
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| Catalog # | 6195/10 |
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| Price | |
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| Order / More Info | SSR 149415 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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