| Edit |   |
| Antigenic Specificity | DIAPH3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl |
| Concentration | n/a |
| Applications | WB. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity). This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3. |
| Immunogen | Human DIAPH3. |
| Other Names | DIAPH3; DIAP3; Protein diaphanous homolog 3; Diaphanous-related formin-3; MDia2; Diaphanous Related Formin 3; DRF3; NSDAN; AUNA1; DIA2; AN; Diaphanous Homolog 3; Diaphanous-Related Formin 3; diaphanous homolog 3 (Drosophila); RP11-26P21.1; DKFZP434C0931; DKFZp686A13178; FLJ34705 |
| Gene, Accession # | DIAPH3, SwissProt: Q9NSV4 |
| Catalog # | abx028919 |
| Price | |
| Order / More Info | DIAPH3 Antibody from ABBEXA |
| Product Specific References | n/a |