产品详情 |
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Antigenic Specificity | Connexin 46 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Connexin 46 Polyclonal Antibody. GJA3, an integral membrane protein, belong to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and nonjunctional ('hemi-') channels. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3), a form of autosomal dominant congenital cataract. |
Immunogen | n/a |
Other Names | Gap junction alpha-3 protein; Connexin-46; Cx46 |
Gene, Accession # | Entrez: 2700; Uniprot: Q9Y6H8 |
Catalog # | PA5-11634 |
Price | |
Order / More Info | Connexin 46 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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