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Product Name | SR 58611A (hydrochloride) |
Description | A selective β3-AR agonist (EC50 = 3.5 nM in rat colon); minimally active against β1-ARs in rat uterus (EC50 = 499 nM) and inactive against β2-ARs in guinea pig trachea and atrium (EC50s = >10,000 and >30,000 nM, respectively); activates brown fat metabolism through activation of adenylyl cyclase activity and glycerol release in brown adipocytes (EC50s = 20 and 11 nM, respectively); reduces hypothermia produced by apomorphine and reserpine; potentiates toxicity produced by yohimbine; reduces number of escape failures in a learned helplessness model of antidepressant-like activity in rats , |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Amibegron |
Gene, Accession, CAS # | CAS: 121524-09-2 |
Catalog # | 11954-10 |
Price | |
Order / More Info | SR 58611A (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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