| 产品详情 |
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| Antigenic Specificity | mGluR1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | mGluR1 Polyclonal Antibody. The Metabotropic Glutamate Receptor mGluR1 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. mGluR1 and mGluR5 are group I receptors that have been shown to activate phospholipase C. Alternative splice variants of the mGluR1 gene have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activatio |
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| Immunogen | n/a |
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| Other Names | GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1, metabotropic glutamate receptor 1 |
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| Gene, Accession # | Entrez: 14816, 24414, 2911; Uniprot: P23385, P97772, Q13255 |
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| Catalog # | PA5-22800 |
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| Price | |
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| Order / More Info | mGluR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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