| 产品详情 |
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| Antigenic Specificity | CD147 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | CF-Blue conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Reacts with basigin or neurothelin, a transmembrane glycoprotein (50-60kd) of the immunoglobulin super-gene family. Neurothelin is a blood brain barrier-specific molecule. It bears homology with mouse gp42 or basigin, human M6 or EmMprin, rat OX-47 or CE-9, and avian HT7 or 5A11. Neurothelin is a molecule which is broadly expressed on cells of hematopoietic and non-hematopoietic origin. Its expression on specific cell types may be regulated by cytokines. CD147 plays a role in embryonal blood-brain barrier development and a role in integrin-mediated adhesion in brain endothelia. Binds to epitope 1 of CD147. CD147 is a single chain type I transmembrane molecule of 269 amino acids (Miyauchi et al. 1991, Kasinrerk et al. 1992, Biswas et al. 1995): 18 amino acids as secretory signal peptide, 187 residue long extracellular region consists of two Ig-like domains of the C2-type, 24 amino acids of transmembrane region and cytoplasmic region has 40 residues. |
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| Immunogen | Activated HUVEC cells. |
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| Other Names | 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen; M6OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD147; Basigin; Leukocyte activation antigen M6; OK blood group antigen; CD antigen CD147; CD147 (Neurothelin); MAB TO CD147; Neurothelin; M6; OK; basigin (Ok blood group); leukocyte activation M6 |
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| Gene, Accession # | Gene ID: 682, SwissProt: P35613 |
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| Catalog # | abx200506 |
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| Price | |
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| Order / More Info | CD147 Antibody from ABBEXA |
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| Product Specific References | n/a |
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