| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Mouse Il12b |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse |
|---|
| Isotype | n/a |
|---|
| Format | peptide affinity purified |
|---|
| Size | 80 µl, 400 µl |
|---|
| Concentration | n/a |
|---|
| Applications | WB. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (By similarity). Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. This Mouse Il12b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-222 amino acids from the Central region of mouse Il12b. |
|---|
| Immunogen | Mouse Il12b. |
|---|
| Other Names | Il12b; Interleukin-12 subunit beta; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL-12 subunit p40 |
|---|
| Gene, Accession # | SwissProt: P43432 |
|---|
| Catalog # | abx030496 |
|---|
| Price | |
|---|
| Order / More Info | Mouse Il12b Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|