| 产品详情 |
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| Antigenic Specificity | ATG13/KIAA0652 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ATG13/KIAA0652 Polyclonal Antibody. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG13 forms a complex with ULK1 and ULK2, the mammalian homologs of ATG1, and with FIP200. This complex is a target of TOR phosphorylation under normal conditions; inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13, ULK1 and ULK2, wh |
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| Immunogen | n/a |
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| Other Names | KIAA0652; autophagy-related protein 13 |
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| Gene, Accession # | Entrez: 51897, 9776; Uniprot: O75143, Q91YI1 |
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| Catalog # | A305-276A-M |
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| Price | |
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| Order / More Info | ATG13/KIAA0652 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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