产品详情 |
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Antigenic Specificity | ATGL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:1000-1:2000, Immunofluorescence: 1:1000-1:2000, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATGL Polyclonal Antibody. Lipolytic enzymes are required for mobilization of fatty acids from triglyceride stores in adipose tissue. Energy homeostasis is affected by dysfunctional lipolysis and may contribute to the pathogenesis of obesity and insulin resistance. Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue. It is now thought that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrola |
Immunogen | n/a |
Other Names | Adipose triglyceride lipase antibody, transport secretion protein (TTS) antibody, desnutrin, calcium-independent phospholipase A2z (iPL-A2z) antibody, |
Gene, Accession # | Entrez: 57104, 66853; Uniprot: Q8BJ56, Q96AD5 |
Catalog # | PA1-16974 |
Price | |
Order / More Info | ATGL Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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