产品详情 |
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Antigenic Specificity | ATG16L1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 4 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATG16L1 Polyclonal Antibody. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG16, another member of the autophagy protein family, forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membr |
Immunogen | n/a |
Other Names | hCG_1817841, APG16L, ATG16A, ATG16L, IBD10, WDR30; APG16L beta; WD repeat domain 30; autophagy-related protein 16-1 |
Gene, Accession # | Entrez: 55054; Uniprot: Q676U5 |
Catalog # | PA5-20482 |
Price | |
Order / More Info | ATG16L1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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