产品详情 |
Edit |   |
Antigenic Specificity | Notch 2 |
Clone | MHN2-25 |
Host Species | Mouse |
Reactive Species | human, African green |
Isotype | IgG2a, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human Notch 2. The Notch receptors are a type I transmembrane protein family that share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. They are highly conserved from invertebrates to mammals. Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors (Notch 1-4). Notch1 and Notch 2 are reported to be functionally redundant. Notch 2 is expressed by Pre-B cells, double negative, and CD8 single positive thymocytes, brain, and lung cells. Notch 2 functions as a receptor for Jagged and Delta ligands and may play a role in vascular, renal and hepatic development. |
Immunogen | Human Notch 2-human IgG1 Fc fusion protein |
Other Names | Neurogenic locus notch homolog protein 2, hN2, fN2 |
Gene, Accession # | Gene ID: 4853 |
Catalog # | 348303 |
Price | |
Order / More Info | Notch 2 Antibody from BIOLEGEND |
Product Specific References | n/a |
产品资料 |
|
|