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| Antigenic Specificity | Notch 2 |
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| Clone | HMN2-35 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-mouse Notch 2. The Notch receptors are highly conserved from invertebrates to mammals.While Notch1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences.The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus.This translocation triggers a series of signaling process.Notch 3 is primarily expressed in adult arterial smooth muscle cells.Notch 3 gene mutation can cause CADASIL, an inherited early stroke syndrome. |
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| Immunogen | Notch 2-Fc fusion protein |
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| Other Names | Neurogenic locus notch homolog protein 2, Notch-2, Notch2, AGS2; hN2 |
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| Gene, Accession # | Gene ID: 18129 |
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| Catalog # | 130714 |
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| Price | |
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| Order / More Info | Notch 2 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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