| 产品详情 |
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| Antigenic Specificity | Notch 1 |
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| Clone | HMN1-12 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-mouse Notch 1. The Notch receptors are highly conserved from invertebrates to mammals. Notch 1 and Notch 2 exhibit the greatest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences. The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. Notch 3 is primarily expressed in adult arterial smooth muscle cells. Notch 3 gene mutation can cause CADASIL, an inherited early stroke syndrome. |
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| Immunogen | Notch1-Fc fusion protein |
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| Other Names | Neurogenic locus notch homolog protein 1, Notch-1, Notch1, TAN1, hN1 |
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| Gene, Accession # | Gene ID: 18128 |
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| Catalog # | 130613 |
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| Price | |
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| Order / More Info | Notch 1 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 24140644 |
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| 产品资料 |
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