产品详情 |
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Antigenic Specificity | CD8 |
Clone | OX-8 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | purified |
Size | 500 ug |
Concentration | n/a |
Applications | Flow Cytometry: 0.1 µg/1x10^6 cells, Immunohistochemistry (Frozen): Assay Dependent, Immunohistochemistry (Paraffin): Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD8 Monoclonal Antibody (OX-8). CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed o |
Immunogen | n/a |
Other Names | CD8, Leu-2, MAL, p32, CD8a, CD8b, CD8alpha, CD8beta |
Gene, Accession # | Entrez: 24930, 24931; Uniprot: P05541, P07725 |
Catalog # | MA5-17394 |
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Order / More Info | CD8 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 11870719, 15030511, 16108823, 16487247, 17206701, 18512246, 27820846, 6416869, 8515082, 9295129, 9973213 |
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