产品详情 |
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Antigenic Specificity | Mu-Calpain |
Clone | 15C10 |
Host Species | Mouse |
Reactive Species | bovine, human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.5-1.0 µg/mL, Immunoprecipitation: 1.0-2.0 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mu-Calpain Monoclonal Antibody (15C10). The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and µ-calpain (calpain I ) are composed of an 80 kD subunit and a 30 kD subunit. Wheras the 30 kD subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. Whereas m-clapain requires millimolar (mM) levels of calcium, µ-calpain is active at micromolar (uM) concentrations of Ca++. In addition to the ubiquitously expressed m- an µ- calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas |
Immunogen | n/a |
Other Names | CaNP |
Gene, Accession # | Entrez: 12333, 281661, 29153, 823; Uniprot: O35350, P07384, P97571, Q27970 |
Catalog # | MA1-12434 |
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Order / More Info | Mu-Calpain Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 28330496 |
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