| 产品详情 |
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| Antigenic Specificity | SCN4B (extracellular) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µl |
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| Concentration | lyophilized |
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| Applications | Immunocytochemistry: 1:50, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1:800 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SCN4B (extracellular) Polyclonal Antibody. The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation By similarity. The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10) [MIM:611819]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event |
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| Immunogen | n/a |
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| Other Names | Sodium channel subunit beta-4 |
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| Gene, Accession # | Entrez: 315611, 399548, 6330; Uniprot: Q7M729, Q7M730, Q8IWT1 |
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| Catalog # | PA5-77742 |
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| Price | |
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| Order / More Info | SCN4B (extracellular) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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