产品详情 |
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Product Name | Imazalil |
Description | An imidazole fungicide that inhibits ergosterol biosynthesis; inhibits the growth of various fungi in vitro including P. italicum, A. niger, U. maydis, B. alii, and C. cucumerinum in a pH-dependent manner (MICs = 0.005-2 µg/ml at pH 7); inhibits S. cerevisiae, but not rat liver microsomal, CYPs (IC50s = 0.088 and 80 µM, respectively), as well as aromatase CYP19 from human placental microsomes (IC50 = 0.34 µM); activates the murine PXR in a concentration-dependent manner in a cell-based reporter assay; increases hepatic CYP3A11 and CYP2B10 mRNA levels in mice at 100 mg/kg; increases Ki-67-positive nuclei in liver sections and hepatic MCM2 mRNA levels, markers of cell proliferation, in mice when co-administered with the mCAR agonist TCPOBOP |
Size | 5 g |
Concentration | n/a |
Applications | n/a |
Other Names | (±)-Imazalil|Enilconazole |
Gene, Accession, CAS # | CAS: 35554-44-0 |
Catalog # | 25815-5 |
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Order / More Info | Imazalil from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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