| 产品详情 |
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| Antigenic Specificity | TAK1/MAP3K7 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: bovine, chicken, monkey, rabbit) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for Mitogen-activated protein kinase kinase kinase 7(MAP3K7) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. Mitogen-activated protein kinase kinase kinase 7, also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human TAK1 (566-603aa RLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQ), identical to the related mouse and rat sequences. |
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| Other Names | Mitogen-activated protein kinase kinase kinase 7;2.7.11.25;Transforming growth factor-beta-activated kinase 1;TGF-beta-activated kinase 1;MAP3K7;TAK1; |
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| Gene, Accession # | MAP3K7, UniProt: O43318 |
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| Catalog # | PB10006 |
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| Price | |
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| Order / More Info | TAK1/MAP3K7 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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