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| Antigenic Specificity | APE1 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 4-6 µg/mL, Immunohistochemistry: 4-6 µg/mL, peptide-ELISA: 1:16000, Western Blot: 0.1-0.3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APE1 Polyclonal Antibody. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. |
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| Immunogen | n/a |
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| Other Names | APEX; APEX1; APEX nuclease (multifunctional DNA repair enzyme); APE; APX; APE1; APEN; HAP1; REF1; REF-1; AP lyase; AP endonuclease class I; apurinic/a |
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| Gene, Accession # | Entrez: 328; Uniprot: P27695 |
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| Catalog # | PA1-9007 |
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| Price | |
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| Order / More Info | APE1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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