产品名称 Interleukin 17A (IL17A) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1513080
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityInterleukin 17A (IL17A)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat, human
Isotypen/a
Formataffinity purified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB),Immunohistochemistry (IHC),Immunofluorescence (IF)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionIL-17A is a cystine-linked homodimeric pro-inflammatory cytokine produced by Th17 cells, a distinct CD4+ T cell lineage. IL-17A stimulates the production of the pro-inflammatory cytokines IL-1beta, TNF-alpha, and IL-6. IL-17A also induces production of the neutrophil chemoattractants IL-8, CXCL1, and CXCL6 thereby bridging adaptive and innate immunity. IL-17A is intimately involved in mucosal immunity against bacterial infections and has a putative role in some autoimmune disorders. IL-17A effects appear to be exerted primarily through binding to the IL-17RA. IL-17A binding induces production of cytokines, chemokines and other proteins through activation of the Erk1/2 MAP kinase, PI3K/Akt, p38, and NF-kappaB pathways (3, 4, 6). Phosphorylation of some Jaks and Stats has been observed.Synonyms: IL17A, CTLA8, IL-17, IL-17A, IL17
ImmunogenRecombinant protein of human IL17A
Other NamesIl17|IL17A|CTLA8|IL-17|IL-17A|IL17|Ctla-8|Ctla8|CTLA-8|ChIL-17|IL-17F
Gene, Accession #Gene ID: 3605,16171,301289
Catalog #ABIN1513080
Price
Order / More InfoInterleukin 17A (IL17A) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 24928352, 25111887
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