产品详情 |
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Antigenic Specificity | KCNIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, human, mouse, porcine, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1:100-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KCNIP1 Polyclonal Antibody. The gene encodes an EF hand-containing small calcium binding protein. It is an integral subunit component of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Kv4 potassium channels regulate action potentials in neurons and cardiac myocytes. The coexpression of ABP with pore-forming Kv4 alpha subunits causes changes in the gating and amplitude of Kv4 currents, thus profoundly affect the intracellular trafficking and molecular properties of Kv4.2 alpha subunits. It also cause a dramatic redistribution of Kv4.2, releasing intrinsic endoplasmic reticulum retention and allowing for trafficking to the cell surface. It may regulate A-type currents, and hence neuronal excitability, in respo |
Immunogen | n/a |
Other Names | KCHIP2, ABP, VABP |
Gene, Accession # | Entrez: 30820, 541458, 595102, 65023, 70357; Uniprot: Q8R426, Q9JJ57, Q9NZI2 |
Catalog # | PA1-41705 |
Price | |
Order / More Info | KCNIP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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