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Product Name | Sennoside A |
Description | A dianthrone glycoside with laxative and gastroprotective activities; increases the amplitude of distal colon contractions in circular and longitudinal muscle and decreases the amplitude of proximal colon contractions in circular muscle ex vivo in mice at 30 mg/kg; increases the gastric emptying rate and increases the intestinal transport rate of a charcoal meal in mice at 100 mg/kg; increases the concentration of PGE2 in AGS gastric cells in vitro; increases gastric juice pH and decreases gastric juice secretion volume and total acid output in pylorus-ligated rats at 100 mg/kg; reduces lesion indices by 43.1 and 36% in HCl?ethanol-induced gastritis and indomethacin-induced gastric ulcer rat models, respectively, at 100 mg/kg; a non-competitive inhibitor of bovine serum monoamine oxidase in vitro (IC50 = 17 µM) |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NSC 112929 |
Gene, Accession, CAS # | CAS: 81-27-6 |
Catalog # | 24969-25 |
Price | |
Order / More Info | Sennoside A from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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