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Product Name | BW A868C |
Description | BW A868C is a hydantoin compound that is structurally related to the DP receptor agonist BW 245C.{1198,3328} BW A868C antagonizes the PGD2 and BW 245C-induced activation of human platelet adenylate cyclase. It reverses the anti-aggregatory effects of DP receptor agonists in a dose-dependent manner. Likewise, BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells.{3804} It has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. The Ki for BW A868C is approximately 1.7 nM.{1254} |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | hydantoin DP receptors antagonists BW245C adenylate cyclase antiaggregatory BWA868C BW-A868C BW-245C prostaglandins PGD2 DP1 |
Gene, Accession, CAS # | CAS: 118675-50-6 |
Catalog # | 12060-1 |
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Order / More Info | BW A868C from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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